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Index > Protein center > ENPP2(Gene name) > Bovine
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  • ENPP2 (Gene name),
  • Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Protein name ),  ENPP2_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ENPP2;
    Protein name:
    Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(E-NPP 2);
    Alternative:
    Extracellular lysophospholipase D(LysoPLD);Autotaxin;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor.
    Subcellular Location:
    Secreted Secreted by most body fluids including serum and CSF. Also by adipocytes and numerous cancer cells.
    Protein Attributes:
    Sequence length:
    888
    Sequence:
    50:
    MARRRSCQLH | QVISLFTFAV | GVNICLGVTA | NRIKRAEGWG | EGPPTVLSDS | 
    100:
    PSINISGSCK | GRCFELQEAG | PPDCRCDNLC | KSYSSCCLDF | DELCLKTAGG | 
    150:
    WECTKDRCGE | VRNEDHACHC | SEDCLARGDC | CTNYQVVCKG | ESHWVDDDCE | 
    200:
    EIKTPECPAG | FVRPPLIIFS | VDGFRASYMK | KGSKVMPNIE | KLRSCGTHSP | 
    250:
    YMRPVYPTKT | FPNLYTLATG | LYPESHGIVG | NSMYDPVFDA | HFNLRGREKF | 
    300:
    NHRWWGGQPL | WITATKQGVI | AGTFFWPVVI | PHERRILTIL | QWLTLPDHER | 
    350:
    PSVYAFYSEQ | PDFSGHKYGP | FGPEMTNPLR | DIDKTVGQLM | DGLKQLKLHR | 
    400:
    CVNVIFVGDH | GMEDVTCDRT | EFLSNYLTNV | DDIILVPGTL | GRIRPKFNNH | 
    450:
    AKYDPKVIIA | NLTCKKPDQH | FKPYLKQHLP | KRLHYANNRR | IEDVHLLVER | 
    500:
    RWHVARKPLE | VYKKPSGKCF | FQGDHGFDNK | VNSMQTVFVG | YGPTFKYKTK | 
    550:
    VPPFENIELY | NVMCDLLGLK | PAPNNGTHGS | LNHLLRTNTF | RPTVPEEVTR | 
    600:
    PNYPGVMYLQ | SDFDLGCTCD | DKAEPKNKLD | ELNKHLHIKE | STEAETRKFR | 
    650:
    GSKNEIKENV | NGNFEPRKER | HLLYGRPAVL | YRTRYDILYH | TDFESGYSEI | 
    700:
    FLMPLWTSYT | VSKQADVSDI | PAHLTNCVRP | DVRVSPSFSQ | SCLAYKNDKQ | 
    750:
    MSYGFLFPPY | LSSSPEAKYD | AFLVTNMVPM | YPAFKRIWNY | FQRVLVKKYA | 
    800:
    SERNGVNVIS | GPIFDYDYDG | LHDTQDKIKQ | YVEGSSVPVP | THYYSILTSC | 
    850:
    LDFTQPADRC | DGPLSVSAFV | LPHRPDNDES | CNSSEDESKW | VEELLKMHTA | 
    888:
    RVRDIEHLTS | LDFFRKTSRS | YPEILTLKTY | LQTYESEI
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine E-NPP 2
    Cat.:
    E1228m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Bovine E-NPP 2
    Cat.:
    E1228h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Bovine E-NPP 2
    Cat.:
    E1228b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Bovine E-NPP 2
    Cat.:
    E1228r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine E-NPP 2
    Cat.:
    U1228b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine E-NPP 2
    Cat.:
    U1228r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine E-NPP 2
    Cat.:
    U1228h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Bovine E-NPP 2
    Cat.:
    U1228m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Bovine E-NPP 2
    Cat.:
    P1228Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine E-NPP 2
    Cat.:
    P1228Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine E-NPP 2
    Cat.:
    P1228Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine E-NPP 2
    Monoclonal Antibody for Bovine E-NPP 2
    Monoclonal Antibody for Bovine E-NPP 2
    Monoclonal Antibody for Bovine E-NPP 2
    Monoclonal Antibody for Bovine E-NPP 2
    Protein for Bovine E-NPP 2
    Protein for Bovine E-NPP 2
    Protein for Bovine E-NPP 2
    Protein for Bovine E-NPP 2

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    References
    1. 1.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2006-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Hereford.
      tissue: Hippocampus.
    2. 2.
      "Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production."
      Umezu-Goto M. , Kishi Y. , Taira A. , Hama K. , Dohmae N. , Takio K. , Yamori T. , Mills G.B. , Inoue K. , Aoki J. , Arai H.
      J. Cell Biol.158:227-233(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 250-266; 749-777 AND 847-866
      tissue: Fetal blood.
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